找到约 30 条 “TAM Receptor” 相关结果 (用时 0.345 秒)
目录号 | 产品名称 | 中文名称 | 靶点 |
---|---|---|---|
M25486 | (S)-(+)-Dimethindene maleate | (S)-(+)-Dimethindene maleate | AChR/AChE |
(S)-(+)-Dimethindene maleate 是一种有效的选择性毒蕈碱 M2 受体拮抗剂 (pA2 = 7.86/7.74; pKi = 7.78)。(S)-(+)-Dimethindene maleate 也是一种组胺 H1 受体 (histamine H1 receptor) 拮抗剂 (pA2 = 7.48)。 | |||
M2088 | Ciproxifan maleate | Ciproxifan maleate | Histamine Receptor |
FUB 359 maleate | |||
Ciproxifan(CPX)是一种高效的,选择性的histamin H3-receptor拮抗剂,IC50为9.2 nM,作用于其他受体亚型具有低亲和力。 | |||
M2180 | SGI-7079 | SGI-7079 | TAM Receptor |
SGI-7079 是一种 ATP-竞争性 Axl 抑制剂,Axl蛋白属于TAM(Tyro3-Axl-Mer)Receptor家族。SGI-7079显著抑制 SUM149 和 KPL-4 细胞增殖,IC50 分别为 0.43 和 0.16 μM。 | |||
M2280 | Tamoxifen Citrate (ICI 46474) | 柠檬酸三苯氧胺;柠檬酸它莫西芬;柠檬酸他莫昔芬 | Estrogen Receptor |
ICI 46474; Istubal; Nolvadex | |||
Tamoxifen Citrate是一种雌激素受体(Estrogen Receptor)拮抗剂,与雌激素竞争性结合。 | |||
M2522 | Ciproxifan | Ciproxifan | Histamine Receptor |
FUB-359 | |||
Ciproxifan(CPX)是一种高效的,选择性的histamin H3-receptor拮抗剂,IC50为9.2 nM,作用于其他受体亚型具有低亲和力。 | |||
M2639 | Dimaprit dihydrochloride | Dimaprit dihydrochloride | Histamine Receptor |
Dimaprit is a histamine type 2 receptor agonist. | |||
M2643 | Diphenylpyraline hydrochloride | 盐酸二苯比拉林;双苯比拉林盐酸盐 | Histamine Receptor |
4-Diphenylmethoxy-1-methylpiperidine hydrochloride | |||
Diphenylpyraline hydrochloride (DPP) is an internationally available antihistamine that produces therapeutic antiallergic effects by binding to histamine H₁ receptors. | |||
M2671 | Epinastine hydrochloride | 依匹斯汀盐酸盐 | Histamine Receptor |
WAL801 hydrochloride | |||
Epinastine HCl是一种抗组胺剂和肥大细胞稳定剂。Epinastine hydrochloride 是一种有效的,选择性的,具有口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。 | |||
M2784 | JNJ-7777120 | JNJ-7777120 | Histamine Receptor |
JNJ-7777120是第一个,有效的,选择性非咪唑histamine H4 receptor拮抗剂,Ki为4.5 nM,比作用于其他组胺受体选择性高1000倍以上。 | |||
M3605 | Salbutamol hemisulfate | 沙丁胺醇半硫酸盐;阿布叔醇 | Adrenergic Receptor |
Albuterol hemisulfate | |||
Salbutamol hemisulfate 是一种短效的β2-肾上腺素能受体(β2 adrenergic receptor)激动剂,IC50为8.93 µM。能用于哮喘和慢性阻塞性肺疾病(COPD)相关研究。 | |||
M5752 | Loratadine | 氯雷他定 | Histamine Receptor |
SCH29851 | |||
Loratadine是一种选择性的histamine H1 receptor拮抗剂,用于治疗过敏。同时还是一种选择性的B(0)AT2抑制剂,其IC50为 4 μM。 | |||
M7353 | Tamoxifen | 他莫昔芬 | Estrogen Receptor |
ICI47699; Z-Tamoxifen; trans-Tamoxifen | |||
Tamoxifen是一种选择性雌激素受体调节剂 (Selective estrogen receptor modulators,SERM),可阻断乳腺细胞中的雌激素作用。Tamoxifen 也是一种有效的 Hsp90 激活剂,可增强 Hsp90 分子伴侣 ATPase 的活性。Tamoxifen 还可以有效抑制传染性 EBOV Zaire 和 Marburg (MARV),IC50 分别为 0.1 µM 和 1.8 µM。 | |||
M7654 | Biphenyl-indanone A | Biphenyl-indanone A | Others |
Biphenyl-indanone A (BINA) is a potent selective positive allosteric modulator for the group II metabotropic glutamate receptor subtype mGluR2. | |||
M7689 | Caroverine hydrochloride | Caroverine hydrochloride | Others |
Caroverine hydrochloride is a nonselective NMDA and AMPA glutamate receptor antagonist. | |||
M7707 | CX546 | CX546 | GluR |
CX-546; GR-87 | |||
CX546 is a selective positive AMPA glutamate receptor modulator. | |||
M7722 | Ciproxifan hydrochloride | 环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯基]甲酮盐酸盐 | Others |
Ciproxifan(CPX) belongs to a novel chemical series of histamine H3-receptor antagonists. | |||
M7741 | DNQX | 二硝基喹酮 | Others |
A competitive kainate, quisqualate (non-NMDA) glutamate receptor antagonist. | |||
M7745 | DCB | DCB | Others |
Neutral allosteric modulator of the metabotropic glutamate receptor mGluR5. | |||
M7766 | Domoic acid | 软骨藻酸 | Others |
Potent agonist at receptors for excitatory amino acids glutamate and kainate; has highest affinity for AMPA/kainate receptor of any kainate agonist; causes excessive excitation of neurons leading to depletion of energy stores. | |||
M7849 | Imetit dihydrobromide | IMETIT氢溴酸盐 | Others |
Potent and selective H3 histamine receptor agonist. | |||
M7856 | Immepip dihydrobromide | Immepip dihydrobromide | Others |
Immepip is a H3 and H4 histamine receptor agonist. | |||
M7881 | LY-487379 hydrochloride | LY-487379 hydrochloride | Others |
LY-487379 is a positive allosteric modulator of the metabotropic glutamate receptor mGluR2. | |||
M7888 | Levocabastine hydrochloride | 左旋多巴 | Others |
Non-peptide histamine H1 receptor antagonist; neurotensin NTS2 receptor ligand. | |||
M7907 | MPPG | MPPG | Others |
Group III/II metabotropic glutamate (mGluR) receptor antagonist. | |||
M7920 | MMPIP | MMPIP | Others |
MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). | |||
M8139 | Ridaifen-B | Ridaifen-B | Others |
Ridaifen-B (RID-B) is a novel tamoxifen (TAM) analog that significantly augments apoptosis-inducing effect of TAM in estrogen receptor (ER)-negatives cells. | |||
M8229 | Conessine | 地麻素;康丝碱;可内新;抗痢夾竹桃鹼;錐絲鹼;锥丝碱;止泻木碱 | Others |
Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5. | |||
M8256 | EAA-090 | EAA-090 | Others |
EAA-090 inhibits the binding of ligands to glutamate receptors and blocks NMDA-induced currents. | |||
M8264 | CDPPB | CDPPB | Others |
Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. | |||
M8367 | Ro 25-6981 maleate salt | Ro 25-6981 maleate salt | GluR |
Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of . |
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